This is why I now use Linux for every single thing I can. Oh, and KnacK, safe mode is pretty useless with a virus if its in task manager, because people who write them would be smart enough to get it to run in there, just like the one I had about 3 months ago because of my idiotic brother.
But in this case it should work in safe-mode, or you have installed something that has played around with your computer.