what does "game can`t follow the mouse" mean, i think you need to be more specific for anyone to help you. describe what you do, what youre used to it doing, and what it is now doing.
also tell us what mouse you have (make and model) and its general type.
with my current wireless mouse/keyboard setup i had a hell of a time getting the keyboard to work right. although it would seem to work fine outside of the game, the game was a much more demanding scenario and allowed me to see that that the wireless receiver was catching every minor stroke. the mouse and keyboard share a receiver, so i had to make a comprimise between the performance of both.