My experiences haven't been great.
1: QWERTY keyboard makes my hands weep. I can't find anywhere to change this.
"Hey, do you know where I can change my keyboard layout?"
"Uhhh... no."
Mac tech support guys apparently only know how to tell you to use photoshop and make new files. UP A LEVEL, to the actual tech support guy
"How can I change keyboard layout?!?"
"Oh, we don't have the permissions set for that. You can't, right now."
"Will you be able to change the permissions?"
"Well, we can't give you access to only part of the control panel..."
Awesome! Now I can't type.
Dubmest permissions ever.
2: The 'Mighty Mouse' or whatever the hell it's called. It doesn't work. I can't click unless I really try to click entirely on the left side of the mouse. HINT: To make a two-button mouse, you need to actually include TWO SEPARATE BUTTONS. The omni-directional scroll ball in the middle is a good idea, but it's so insensitive that I felt like I was about to get carpal tunnel after about two minutes of working on something I had to scroll to the left and/or right with. Maybe you can change the sensitivity in the prefs panel, but I CAN'T GET TO ANY OF THAT.
Also, the thumb buttons trigger at the lightest touch. That gets really annoying while trying to do some precision photoshop work. I actually brought my own mouse, discovered you could daisy-chain the keyboards, and set up my mouse connected about ten keyboards down, just for fun. Mac tech guy wasn't very happy, but I put everything back and not many other people were there.